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95 Furthermore, other literature suggests that JS-K inhibits angiogenesis, 96 induces cell apoptosis (a process related to PARP, caspase 8 and 9 cleavage, and cell differentiation), 95,97 destroys double-stranded DNA, 95,9799 and is also able to interfere with the cell cycle and its respective signaling pathways

However, prioritizing non-pregnant subjects outside the extremes of age decreases the likelihood of unforeseen confounding variables

Collectively, these results indicated that RhoA was upregulated in the subchondral bone remodeling phase of OA

Nguyen-Ngo C, Perkins AV, Lappas M

Vitamin D and its effects on articular cartilage and osteoarthritis

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